Which rule specifies the response of the give-way vessel?

Rule 16 is the rule that specifies the responsibilities of the give-way vessel in a situation where two vessels are approaching each other. This rule states that the give-way vessel must take early and substantial action to avoid collision. It is essential for the safety of navigation that the give-way vessel can recognize its obligation to yield, thus allowing the stand-on vessel to maintain its course and speed.

This rule emphasizes the importance of communication and awareness on the water, ensuring that vessels can avoid potential collisions by clearly defining who should take action to prevent an incident. Understanding the specifics of Rule 16 enhances a mariner's ability to navigate safely and responsibly in various marine situations.